Hovingh, Kees G.: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Genetic variation in APOB, PCSK9, and ANGPTL3 in carriers of pathogenic autosomal dominant hypercholesterolemic mutations with unexpected low LDL-Cl Levels

Roeland Huijgen, Barbara Sjouke, Kelly Vis, Janine S.E. de Randamie, Joep C. Defesche, John J.P. Kastelein, G. Kees Hovingh, Sigrid W. Fouchier

Journal:

Year:

2012

Language:

english

File:

PDF, 177 KB

english, 2012

2

Lipid-Modifying Agents, FromÂ StatinsÂ toÂ PCSK9 Inhibitors

Preiss, David, Tobert, Jonathan A., Hovingh, G. Kees, Reith, Christina

Journal:

Journal of the American College of Cardiology

Year:

2020

File:

PDF, 814 KB

2020

3

Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial

Raal, Frederick J, Honarpour, Narimon, Blom, Dirk J, Hovingh, G Kees, Xu, Feng, Scott, Rob, Wasserman, Scott M, Stein, Evan A

Journal:

Year:

2015

Language:

english

File:

PDF, 274 KB

english, 2015

4

Selection of individuals for genetic testing for familial hypercholesterolaemia: development and external validation of a prediction model for the presence of a mutation causing familial hypercholesterolaemia

Besseling, Joost, Reitsma, Johannes B., Gaudet, Daniel, Brisson, Diane, Kastelein, John J.P., Hovingh, G. Kees, Hutten, Barbara A.

Journal:

European Heart Journal

Year:

2016

Language:

english

File:

PDF, 267 KB

english, 2016

5

Familial hypercholesterolemia treatments: Guidelines and new therapies

Raal, Frederick J., Hovingh, G. Kees, Catapano, Alberico L.

Journal:

Atherosclerosis

Year:

2018

Language:

english

File:

PDF, 411 KB

english, 2018

6

High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in the Netherlands: Identification and characterization of eight novel mutations

Adriaan G. Holleboom, Jan A. Kuivenhoven, Frank Peelman, Alinda W. Schimmel, Jorge Peter, Joep C. Defesche, John J.P. Kastelein, G. Kees Hovingh, Erik S. Stroes, Mohammad Mahdi Motazacker

Journal:

Year:

2011

Language:

english

File:

PDF, 337 KB

english, 2011

7

Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection

Herman, Daniel S, Hovingh, G Kees, Iartchouk, Oleg, Rehm, Heidi L, Kucherlapati, Raju, Seidman, J G, Seidman, Christine E

Journal:

Year:

2009

Language:

english

File:

PDF, 390 KB

english, 2009

8

The Genetics of High-Density Lipoprotein Metabolism: Clinical Relevance for Therapeutic Approaches

Aart C. Strang, G. Kees Hovingh, Erik S.G. Stroes, John J.P. Kastelein

Journal:

The American Journal of Cardiology

Year:

2009

Language:

english

File:

PDF, 595 KB

english, 2009

9

Patients with low HDL-cholesterol caused by mutations in LCAT have increased arterial stiffness

van den Bogaard, Bas, Holleboom, Adriaan G., Duivenvoorden, Raphaël, Hutten, Barbara A., Kastelein, John J.P., Hovingh, G. Kees, Kuivenhoven, Jan Albert, Stroes, Erik S.G., van den Born, Bert-Jan H.

Journal:

Atherosclerosis

Year:

2012

Language:

english

File:

PDF, 258 KB

english, 2012

10

Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1, APOA1, and LCAT

Ian Tietjen, G. Kees Hovingh, Roshni Singaraja, Chris Radomski, Jason McEwen, Elden Chan, Maryanne Mattice, Annick Legendre, John J.P. Kastelein, Michael R. Hayden

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2012

Language:

english

File:

PDF, 993 KB

english, 2012

11

Effects of short-term and long-term danazol treatment on lipoproteins, coagulation, and progression of atherosclerosis: Two clinical trials in healthy volunteers and patients with hereditary angioedema

Rakesh S. Birjmohun, G. Kees Hovingh, Erik S.G. Stroes, Jorit J. Hofstra, Geesje M. Dallinga-Thie, Joost C.M. Meijers, John J.P. Kastelein, Marcel Levi

Journal:

Clinical Therapeutics

Year:

2008

Language:

english

File:

PDF, 1020 KB

english, 2008

12

Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study

Marjel J van Dam, Eric de Groot, Susanne M Clee, G Kees Hovingh, Roosje Roelants, Angie Brooks-Wilson, Aeilko H Zwinderman, Andries J Smit, August HM Smelt, Albert K Groen, Michael R Hayden, John JP K

Journal:

Year:

2002

Language:

english

File:

PDF, 173 KB

english, 2002

13

The cholesterol content of the erythrocyte membrane is an important determinant of phosphatidylserine exposure

Rob van Zwieten, Andrea E. Bochem, Petra M. Hilarius, Robin van Bruggen, Ferry Bergkamp, G. Kees Hovingh, Arthur J. Verhoeven

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2012

Language:

english

File:

PDF, 551 KB

english, 2012

14

Reduced fecal sterol excretion in subjects with familial hypoalphalipoproteinemia

Karim El Harchaoui, Remco Franssen, G. Kees Hovingh, Radjesh J. Bisoendial, Frans Stellaard, Folkert Kuipers, John J.P. Kastelein, Jan Albert Kuivenhoven, Erik S.G. Stroes, Albert K. Groen

Journal:

Atherosclerosis

Year:

2009

Language:

english

File:

PDF, 170 KB

english, 2009

15

A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease

G. Kees Hovingh, Alison Brownlie, Radjesh J. Bisoendial, Marie Pierre Dube, Johannes H.M. Levels, Wilma Petersen, Robin P.F. Dullaart, Erik S.G. Stroes, Aeilko H. Zwinderman, Eric de Groot, Michael R.

Journal:

Journal of the American College of Cardiology

Year:

2004

Language:

english

File:

PDF, 150 KB

english, 2004

16

Cholesterol Acyltransferase Gene Mutations Have Accelerated Atherogenesis as Assessed by Carotid 3.0-T Magnetic Resonance Imaging: Carriers of Lecithin

Raphaël Duivenvoorden, Adriaan G. Holleboom, Bas van den Bogaard, Aart J. Nederveen, Eric de Groot, Barbara A. Hutten, Alinda W. Schimmel, G. Kees Hovingh, John J.P. Kastelein, Jan Albert Kuivenhoven,

Journal:

Journal of the American College of Cardiology

Year:

2011

Language:

english

File:

PDF, 306 KB

english, 2011

17

Genetics of HDL-C: A Causal Link to Atherosclerosis?

Capelleveen, Julian C., Bochem, Andrea E., Motazacker, M. Mahdi, Hovingh, G. Kees, Kastelein, John J. P.

Journal:

Current Atherosclerosis Reports

Year:

2013

Language:

english

File:

PDF, 218 KB

english, 2013

18

Efficacy and safety of mipomersen sodium (Kynamro)

Hovingh, Kees, Besseling, Joost, Kastelein, John

Journal:

Expert Opinion on Drug Safety

Year:

2013

Language:

english

File:

PDF, 544 KB

english, 2013

19

LDL Cholesterol Goals in High-Risk Patients: How Low Do We Go and How Do We Get There?

Joost Besseling, Julian van Capelleveen, John J. P. Kastelein, G. Kees Hovingh

Journal:

Year:

2013

Language:

english

File:

PDF, 323 KB

english, 2013

20

Severe heterozygous familial hypercholesterolemia and risk for cardiovascular disease: A study of a cohort of 14,000 mutation carriers

Besseling, Joost, Kindt, Iris, Hof, Michel, Kastelein, John J.P., Hutten, Barbara A., Hovingh, G. Kees

Journal:

Atherosclerosis

Year:

2014

Language:

english

File:

PDF, 306 KB

english, 2014

21

HDL does not influence the polarization of human monocytes toward an alternative phenotype

Colin, Sophie, Fanchon, Mélanie, Belloy, Loic, Bochem, Andrea E., Copin, Corinne, Derudas, Bruno, Stroes, Erik S.G., Hovingh, G. Kees, Kuivenhoven, Jan A., Dallinga-Thie, Geesje M., Staels, Bart, Chin

Journal:

International Journal of Cardiology

Year:

2014

File:

PDF, 396 KB

2014

22

THE TRP719ARG VARIANT OF KIF6 AND CARDIOVASCULAR OUTCOMES IN STATIN-TREATED, CORONARY STABLE PATIENTS OF THE TNT AND IDEAL PROSPECTIVE STUDIES

Arsenault, Benoit, Boekholdt, S. Matthijs, Hovingh, G. Kees, Hyde, Craig L., DeMicco, David A., Chatterjee, Aurobindo L., Barter, Philip, Deedwania, Prakash, Waters, David D., LaRosa, John C., Pederse

Journal:

Journal of the American College of Cardiology

Year:

2011

Language:

english

File:

PDF, 241 KB

english, 2011

23

Lysosomal acid lipase deficiency – An under-recognized cause of dyslipidaemia and liver dysfunction

Reiner, Željko, Guardamagna, Ornella, Nair, Devaki, Soran, Handrean, Hovingh, Kees, Bertolini, Stefano, Jones, Simon, Ćorić, Marijana, Calandra, Sebastiano, Hamilton, John, Eagleton, Terence, Ros, Emi

Journal:

Atherosclerosis

Year:

2014

Language:

english

File:

PDF, 1018 KB

english, 2014

24

Eprotirome in patients with familial hypercholesterolaemia (the AKKA trial): a randomised, double-blind, placebo-controlled phase 3 study

Sjouke, Barbara, Langslet, Gisle, Ceska, Richard, Nicholls, Stephen J, Nissen, Steven E, Öhlander, Maria, Ladenson, Paul W, Olsson, Anders G, Hovingh, G Kees, Kastelein, John J P

Journal:

The Lancet Diabetes & Endocrinology

Year:

2014

Language:

english

File:

PDF, 164 KB

english, 2014

25

THERAPY WITH THE THYROID HORMONE RECEPTOR AGONIST EPROTIROME IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA: RESULTS OF THE AKKA TRIAL

Sjouke, Barbara, Langslet, Gisle, Ceska, Richard, Nicholls, Stephen, Nissen, Steven, Öhlander, Maria, Ladenson, Paul, Olsson, Anders, Hovingh, G Kees, Kastelein, John

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 179 KB

english, 2014

26

Statin and the Risk of Renal-Related Serious Adverse Events: Analysis from the IDEAL, TNT, CARDS, ASPEN, SPARCL, and Other Placebo-Controlled Trials

Bangalore, Sripal, Fayyad, Rana, Hovingh, G. Kees, Laskey, Rachel, Vogt, Liffert, DeMicco, David A., Waters, David D.

Journal:

The American Journal of Cardiology

Year:

2014

Language:

english

File:

PDF, 216 KB

english, 2014

27

Very Low Levels of Atherogenic Lipoproteins and the Risk for Cardiovascular Events

Boekholdt, S. Matthijs, Hovingh, G. Kees, Mora, Samia, Arsenault, Benoit J., Amarenco, Pierre, Pedersen, Terje R., LaRosa, John C., Waters, David D., DeMicco, David A., Simes, R. John, Keech, Antony C

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 522 KB

english, 2014

28

HDL and cardiovascular disease

Rader, Daniel J, Hovingh, G Kees

Journal:

Year:

2014

Language:

english

File:

PDF, 493 KB

english, 2014

29

The Value of Screening for Carotid Plaque in Patients Referred for Echocardiography

Duivenvoorden, Raphael, Stroes, Erik S.G., Hovingh, G. Kees

Journal:

Canadian Journal of Cardiology

Year:

2014

Language:

english

File:

PDF, 264 KB

english, 2014

30

PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial

Raal, Frederick J, Stein, Evan A, Dufour, Robert, Turner, Traci, Civeira, Fernando, Burgess, Lesley, Langslet, Gisle, Scott, Russell, Olsson, Anders G, Sullivan, David, Hovingh, G Kees, Cariou, Bertra

Journal:

Year:

2015

Language:

english

File:

PDF, 361 KB

english, 2015

31

ApoA-I mutations, L202P and K131del, in HDL from heterozygotes with low HDL-C

Ljunggren, Stefan, Levels, Johannes H. M., Turkina, Maria V., Sundberg, Sofie, Bochem, Andrea E., Hovingh, Kees, Holleboom, Adriaan G., Lindahl, Mats, Kuivenhoven, Jan Albert, Karlsson, Helen

Journal:

PROTEOMICS - Clinical Applications

Year:

2014

Language:

english

File:

PDF, 254 KB

english, 2014

32

Annexin A5 haplotypes in familial hypercholesterolemia: Lack of association with carotid intima-media thickness and cardiovascular disease risk

Hiddink, Larissa, Dallinga-Thie, Geesje M., Hovingh, G. Kees, de Visser, Marieke C.H., Peer, Petronella G.M., Stalenhoef, Anton F.H., van Heerde, Waander L.

Journal:

Atherosclerosis

Year:

2015

Language:

english

File:

PDF, 252 KB

english, 2015

33

Analysis of vitamin D levels in patients with and without statin-associated myalgia — A systematic review and meta-analysis of 7 studies with 2420 patients

Michalska-Kasiczak, Marta, Sahebkar, Amirhossein, Mikhailidis, Dimitri P., Rysz, Jacek, Muntner, Paul, Toth, Peter P., Jones, Steven R., Rizzo, Manfredi, Kees Hovingh, G., Farnier, Michel, Moriarty, P

Journal:

International Journal of Cardiology

Year:

2015

Language:

english

File:

PDF, 492 KB

english, 2015

34

Reply

Boekholdt, S. Matthijs, Hovingh, G. Kees, Waters, David D., Grundy, Scott M., Kastelein, John J.P.

Journal:

Journal of the American College of Cardiology

Year:

2015

Language:

english

File:

PDF, 89 KB

english, 2015

35

Common genetic variants do not associate with CAD in familial hypercholesterolemia

van Iperen, Erik P A, Sivapalaratnam, Suthesh, Boekholdt, S Matthijs, Hovingh, G Kees, Maiwald, Stephanie, Tanck, Michael W, Soranzo, Nicole, Stephens, Jonathan C, Sambrook, Jennifer G, Levi, Marcel,

Journal:

European Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 320 KB

english, 2014

36

The effect of an apolipoprotein A-I–containing high-density lipoprotein–mimetic particle (CER-001) on carotid artery wall thickness in patients with homozygous familial hypercholesterolemia

Hovingh, G. Kees, Smits, Loek P., Stefanutti, Claudia, Soran, Handrean, Kwok, See, de Graaf, Jacqueline, Gaudet, Daniel, Keyserling, Constance H., Klepp, Heather, Frick, Jennifer, Paolini, John F., Da

Journal:

American Heart Journal

Year:

2015

Language:

english

File:

PDF, 375 KB

english, 2015

37

Treatment of Low HDL-C Subjects with the CETP Modulator Dalcetrapib Increases Plasma Campesterol Only in Those WithoutABCA1and/orApoA1Mutations

Niesor, Eric J., Kallend, David, Bentley, Darren, Kastelein, John J. P., Kees Hovingh, G., Stroes, Erik S. G.

Journal:

Year:

2014

Language:

english

File:

PDF, 445 KB

english, 2014

38

Anacetrapib as lipid-modifying therapy in patients with heterozygous familial hypercholesterolaemia (REALIZE): a randomised, double-blind, placebo-controlled, phase 3 study

Kastelein, John J P, Besseling, Joost, Shah, Sukrut, Bergeron, Jean, Langslet, Gisle, Hovingh, G Kees, Al-Saady, Naab, Koeijvoets, Michiel, Hunter, John, Johnson-Levonas, Amy O, Fable, Jennifer, Sapre

Journal:

Year:

2015

Language:

english

File:

PDF, 292 KB

english, 2015

39

Association Between Familial Hypercholesterolemia and Prevalence of Type 2 Diabetes Mellitus

Besseling, Joost, Kastelein, John J. P., Defesche, Joep C., Hutten, Barbara A., Hovingh, G. Kees

Journal:

JAMA The Journal of the American Medical Association

Year:

2015

Language:

english

File:

PDF, 278 KB

english, 2015

40

HDL re-examined

Hovingh, G. Kees, Rader, Daniel J., Hegele, Robert A.

Journal:

Current Opinion in Lipidology

Year:

2015

Language:

english

File:

PDF, 221 KB

english, 2015

41

Recent failures in antiatherosclerotic drug development

Stoekenbroek, Robert M., Kastelein, John J.P., Hovingh, G. Kees

Journal:

Current Opinion in Lipidology

Year:

2013

Language:

english

File:

PDF, 242 KB

english, 2013

42

Genetic Variant of the Scavenger Receptor BI in Humans

Vergeer, Menno, Korporaal, Suzanne J.A., Franssen, Remco, Meurs, Illiana, Out, Ruud, Hovingh, G. Kees, Hoekstra, Menno, Sierts, Jeroen A., Dallinga-Thie, Geesje M., Motazacker, Mohammad Mahdi, Hollebo

Journal:

Boston Medical and Surgical Journal

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

43

A rare variant in MCF2L identified using exclusion linkage in a pedigree with premature atherosclerosis

Maiwald, Stephanie, Motazacker, Mahdi M, van Capelleveen, Julian C, Sivapalaratnam, Suthesh, van der Wal, Allard C, van der Loos, Chris, Kastelein, John J P, Ouwehand, Willem H, Hovingh, G Kees, Trip,

Journal:

European Journal of Human Genetics

Year:

2015

Language:

english

File:

PDF, 1.55 MB

english, 2015

44

Prevalence and management of familial hypercholesterolaemia in coronary patients: An analysis of EUROASPIRE IV, a study of the European Society of Cardiology

De Backer, Guy, Besseling, Joost, Chapman, John, Hovingh, G.Kees, Kastelein, John J.P., Kotseva, Kornelia, Ray, Kausik, Reiner, Željko, Wood, David, De Bacquer, Dirk

Journal:

Atherosclerosis

Year:

2015

Language:

english

File:

PDF, 416 KB

english, 2015

45

PCSK9 inhibitors: Novel therapeutic agents for the treatment of hypercholesterolemia

Verbeek, Rutger, Stoekenbroek, Robert M., Hovingh, G. Kees

Journal:

European Journal of Pharmacology

Year:

2015

Language:

english

File:

PDF, 540 KB

english, 2015

46

Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial

Hovingh, G Kees, Kastelein, John J P, van Deventer, Sander J H, Round, Patrick, Ford, John, Saleheen, Danish, Rader, Daniel J, Brewer, H Bryan, Barter, Philip J

Journal:

Year:

2015

Language:

english

File:

PDF, 460 KB

english, 2015

47

Is Cholesteryl Ester Transfer Protein Inhibition an Effective Strategy to Reduce Cardiovascular Risk?Response to Hovingh et al

Hovingh, G. Kees, Ray, Kausik K., Boekholdt, S. Matthijs

Journal:

Year:

2015

Language:

english

File:

PDF, 681 KB

english, 2015

48

The impact of LDLR function on fibroblast growth factor 21 levels

Besseling, Joost, Ong, Kwok Leung, Huijgen, Roeland, Rye, Kerry-Anne, Hovingh, G.Kees, Hutten, Barbara A., Lambert, Gilles

Journal:

Atherosclerosis

Year:

2015

Language:

english

File:

PDF, 213 KB

english, 2015

49

Familial hypercholesterolaemia: A global call to arms

Vallejo-Vaz, Antonio J., Kondapally Seshasai, Sreenivasa Rao, Cole, Della, Hovingh, G. Kees, Kastelein, John J.P., Mata, Pedro, Raal, Frederick J., Santos, Raul D., Soran, Handrean, Watts, Gerald F.,

Journal:

Atherosclerosis

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

50

Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein

V. Sorrentino, S. W. Fouchier, M. M. Motazacker, J. K. Nelson, J. C. Defesche, G. M. Dallinga-thie, J. J. P. Kastelein, G. Kees Hovingh, N. Zelcer

Year:

2013

Language:

english

File:

PDF, 254 KB

english, 2013